McKesson Plans $179 Million Distribution Center in Oklahoma

Why This Matters to Distributors: The project reflects continued investment in automation, cold-chain infrastructure and supply chain resilience as distributors expand capacity to support growing demand for pharmaceuticals and other healthcare products.

McKesson Corp. plans to build a $179 million pharmaceutical distribution center in Moore, Oklahoma, expanding its U.S. distribution network with a highly automated facility designed to serve customers across Oklahoma, Texas, and the surrounding region.

The 330,000-square-foot facility will replace the existing McKesson distribution center and create more than 200 jobs, according to an announcement from the Oklahoma Department of Commerce and the Cleveland County Economic Development Coalition.

McKesson said the facility will include automated material-handling systems, digital logistics technology, precision inventory management and expanded cold-chain storage capacity. The distribution center also will feature 100% standby power to support operations during disruptions.

“The healthcare supply chain grows more complex, from supporting advanced therapies with specialized handling and storage to navigating modernization, security and supply constraints,” Gene Cavacini, president of U.S. Pharmaceutical Distribution at McKesson. “This investment strengthens our ability to deliver with speed, precision and resilience, while expanding capacity to better serve Oklahoma, Texas and the surrounding region.”

McKesson said it distributes approximately one-third of the pharmaceuticals used in North America through a network serving pharmacies, hospitals, and other healthcare providers.

The Cleveland County Economic Development Coalition said the project is expected to generate more than 200 direct jobs and produce an estimated $118 million annual economic impact when fully operational.

Construction is scheduled to begin in 2026 and continue through 2028.

The investment is the latest example of distributors expanding automated distribution capacity as healthcare supply chains require greater throughput, temperature-controlled storage, and operational redundancy to support the delivery of specialty medications and other high-value products.

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